This study discusses the effects of integrated psychological treatment in hospitalized patients with schizophrenia in Lebanon. Cognitive impairments are considered as one of the core deficits in patients with schizophreniThey induce major disturbance in psychosocial functioning, inhibit professional and scholarly achievement, and diminish subjective quality of life. The results of this study demonstrate that Integrated Psychological Treatment Program (IPT) showed better efficacy than usual treatment to improve cognitive deficits in patients with schizophreniThis program also produces a decrease in positive and, most importantly, negative symptoms of schizophrenia as well as improvement in social adaptation. The current pharmacological treatments for schizophrenia are only moderately effective against these symptoms. IPT should be considered as a relevant add-on therapy to manage persistent and enduring symptoms of schizophreniMoreover, the current study is among the first to demonstrate the effectiveness of IPT in severely ill patients, since they are hospitalized for several years. The results show that the IPT is beneficial for patients with a high level of symptoms suffering from severe chronicity. These patients were able to learn and use skills essential to a good functioning in daily life.