Objectives: The aim of this article is to facilitate genetic research in mental health in the Arab world through a specific interview designed for this purpose and used internationally mainly the Arabic Diagnostic Interview for Genetic Studies. Methods: The original English Diagnostic Interview for Genetic Studies (DIGS) was translated and adapted to Arabic by two teams from Lebanon and Qatar. It was successfully field tested in both countries in an ongoing genetic study. Conclusion: The Arabic DIGS is now available in the Arab world and has been field tested by both the Lebanese and the Qatar teams and should be easy for use by Arab researchers. A preview of the Arabic DIGS can be seen at IDRAAC website www.idraac.org (search for DIGS).