Objective: To examine the association between gestational diabetes and postpartum depression. Study design:A prospective study was conducted using Edinburgh Postnatal Depression Scale (EPDS) for all postpartum women with gestational diabetes and a control sample (women who gave birth in the same period without gestational diabetes), over the period (January 1st /2001 to March 31st /2001).Setting: Abha maternity hospital. ABHA, Saudi Arabia. Results: In this study we found that the possible diagnosis of postpartum depression was found in 20.35 % of those with gestational diabetes compared with 18.58 % in those without gestational diabetes, which was statistically not significant. The overall possible post-partum depression in both(study and control samples) was 44 out of 113 patients (38.9 %).Conclusion: A similar and high rate of postpartum depression was found in women with gestational diabetes and those without gestational diabetes.