Neuroleptic-induced tardive dyskinesia among Arab psychotic patients
Author: Osman A, Marghalani M, Turkistani IY, Al Swaf M, Bin Sadiq B
Source:
EMHJ-Eastern Mediterranean Health Journal, 13 (3), 625-632, 2007.
We carried out a retrospective descriptive study to determine prevalence and risk
factors for tardive dyskinesia (TD) among psychotic patients treated with
conventional neuroleptics in 4 centres in Saudi ArabiRecords of patients who
had been taking > or = 1 conventional neuroleptic for > or = 6 months from
January 1997 to December 2000 were examined; 151 patients were included in the
final analysis. Only 51 had TD; another 59 (6.8%) patients had drug-induced
Parkinson disease. Duration of treatment (P < 0.001), higher doses of
neuroleptics (P < 0.01) and age over 40 years (P < 0.01) were associated with TD.
A statistically significant difference in prevalence was found between Arabs
(23.5%) and Afro-Arabs (45.5%) (P < 0.01). Overall prevalence of TD among
psychotic patients was 5.9%.