This study investigated the acculturation experiences of East Asian immigrants in the United States. The framework employed in this study was developed by Barry (1996) to assess the acculturation experiences of male Arab immigrants in the U.S. Key variables examined included acculturation patterns, ethnic identity, self-construal, and mental health. Based on pilot interview data and selected items from preexisting measures, an East Asian Acculturation Measure (EAAM) and an East Asian Ethnic Identity Scale (EAEIS) were developed using a sample of 150 East Asian immigrants. Satisfactory reliability was reported for the four scales of the EAAM, Separation, Assimilation, Marginalization, and Integration, and the EAEIS as well as its three scales, including Family Values, Ethnic Pride (Language, Sense of Belonging) and Interpersonal Distance. The EAAM and EAEIS were then used to investigate the relationships between self-construal, ethnic identity, acculturation, and mental health, which comprised self-esteem and psychological distress. Results included the following: East Asian immigrants who scored high on ethnic identity tended to have a more interdependent sense of self than those who scored lower on East Asian ethnic identity. Participants who adopted a separation acculturation style tended to endorse a strong ethnic identity and were less likely to have a salient independent self-construal, whereas assimilated and integrated participants tended to have a weaker ethnic identity and a salient independent self-construal. Ethnic identity, acculturation, and self-construal were all related to mental health in this study. Ethnic identity was found to relate to collective self-esteem but not to reported psychological distress. Marginalized East Asians appeared to demonstrate relatively poor mental health. Individuals who reported high independent self-construal scores displayed low collective self-esteem but did not report significant psychological distress, whereas respondents who scored high on interdependent self-construal reported high collective self-esteem but also reported significant psychological distress. The CSE appeared to be a more sensitive measure of well being than the Rosenberg in this population. A three-factor framework, which includes self-construal, ethnic identity, and acculturation, is discussed in terms of clinical and research potential. In particular, it is suggested that the acculturation (EAAM) and (EAEIS) measures may be useful in further research with East Asian populations.