The influence of acculturation processes on adverse changes in BP, a major risk factor for cardiovascular disease (CVD), is examined in Chaldean-American, a major subgroup of the large Arab-American population located in metropolitan Detroit, Michigan. Ss were 130 Chaldean-American women aged 35-45 yrs old. Physical measurements included BP, body mass index (BMI), and waist-hip ratio. Demographic and acculturation data were obtained through a standardized questionnaire. The crude hypertension prevalence in the sample was 16%. Three dimensions of acculturation were identified: English language preference, parental school involvement, and ethnic identity. In unadjusted analyses, both English language preference and Chaldean-American ethnic identity were associated with lower mean BP, but these differences became nonsignificant when age, BMI, and waist-hip ratio were statistically controlled. Parental school involvement was not associated with BP in any analyses. The strongest predictors of BP were BMI and waist-hip ratio, both of which were inversely correlated with age, education, English language preference, employment outside the home, and parental school involvement. Implications for future research with Arab-Americans are discussed.