Investigated the psychometric properties and predictive validity of the Arabic translation of the Edinburgh Postnatal Depression Scale (EPDS). 95 postpartum women (mean age 28.6 yrs) were assessed at 1 wk postpartum with the 2 wks postpartum using the Present State Examination (PSE). A ± EPDS and at 8 moderate correlation between PSE total score and EPDS score was found. A moderate agreement between EPDS and Catego diagnosis of depression was also found. Using a cut-off score of 12 on the EPDS and Catego diagnosis as a criterion variable, the sensitivity and specificity of the scale were 73% and 90%, respectively. However, using a cut-off score of 10, the sensitivity of the scale rose to 91% without much fall in its specificity (84%). The internal reliability of the scale was 0.84.