Examined 73 Ss (41 females) with headaches to evaluate different types of headaches and to examine the possible role of hormonal profiles on underlying psychological factors. 35 Ss (12 females) without headaches served as controls. Ss with headaches suffered from either migraines, chronic tension headaches (CTHs), or tension-type headaches (TTHs) with underlying depression. All Ss completed the Eysenck Personality Questionnaire (EPQ). Evaluation identified psychological profiles and personalities of Ss with headaches. Ss with headaches were more neurotic, anxious, and depressed than control Ss. Men with migraines were more neurotic, anxious, and depressed than were women with migraines. In Ss with CTH, men were more neurotic, and women were more depressed. Men with TTH were more neurotic, anxious, and introverted than women with TTH. Hormonal changes contributed to the psychometric profile characterizing various headache types.